Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension
Purpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry an...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2013/463710 |
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| author | Rita A. Gangwani Jonathan Chan Jacky Lee Alfred Kwong Jimmy S. M. Lai |
| author_facet | Rita A. Gangwani Jonathan Chan Jacky Lee Alfred Kwong Jimmy S. M. Lai |
| author_sort | Rita A. Gangwani |
| collection | DOAJ |
| description | Purpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with IOP>21 mmHg and/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR). Results. The mean age of the subjects was 64.66±9.47 years, and the male:female ratio was 92 : 108. All patients were hypertensive with a mean blood pressure (BP) of 131.1±15.1/76.6±11.1 mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%. Conclusion. Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type. |
| format | Article |
| id | doaj-art-9fedfd04af134313a94c4728aa5fa9b7 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-9fedfd04af134313a94c4728aa5fa9b72025-02-03T01:24:07ZengWileyJournal of Ophthalmology2090-004X2090-00582013-01-01201310.1155/2013/463710463710Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic HypertensionRita A. Gangwani0Jonathan Chan1Jacky Lee2Alfred Kwong3Jimmy S. M. Lai4Department of Ophthalmology, The University of Hong Kong, Hong KongDepartment of Ophthalmology, Queen Mary Hospital, Hong KongDepartment of Ophthalmology, The University of Hong Kong, Hong KongDepartment of Family Medicine, Hospital Authority, Hong KongDepartment of Ophthalmology, The University of Hong Kong, Hong KongPurpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with IOP>21 mmHg and/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR). Results. The mean age of the subjects was 64.66±9.47 years, and the male:female ratio was 92 : 108. All patients were hypertensive with a mean blood pressure (BP) of 131.1±15.1/76.6±11.1 mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%. Conclusion. Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type.http://dx.doi.org/10.1155/2013/463710 |
| spellingShingle | Rita A. Gangwani Jonathan Chan Jacky Lee Alfred Kwong Jimmy S. M. Lai Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension Journal of Ophthalmology |
| title | Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension |
| title_full | Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension |
| title_fullStr | Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension |
| title_full_unstemmed | Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension |
| title_short | Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension |
| title_sort | detection of glaucoma in a cohort of chinese subjects with systemic hypertension |
| url | http://dx.doi.org/10.1155/2013/463710 |
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