Exploring the Interaction of Biotinylated FcGamma RI and IgG1 Monoclonal Antibodies on Streptavidin-Coated Plasmonic Sensor Chips for Label-Free VEGF Detection

Exploring the Interaction of Biotinylated FcGamma RI and IgG1 Monoclonal Antibodies on Streptavidin-Coated Plasmonic Sensor Chips for Label-Free VEGF Detection

Vascular endothelial growth factor (VEGF) is a critical angiogenesis biomarker associated with various pathological conditions, including cancer. This study leverages pre-biotinylated FcγRI interactions with IgG1-type monoclonal antibodies to develop a sensitive VEGF detection method. Utilizing surf...

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Bibliographic Details
Main Authors: Soodeh Salimi Khaligh, Fahd Khalid-Salako, Hasan Kurt, Meral Yüce
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biosensors
Subjects:
VEGF biosensor
FcγRI
monoclonal antibodies
surface plasmon resonance (SPR)
biosensing technology
Online Access:https://www.mdpi.com/2079-6374/14/12/634
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