Dysfunction of Telomeric Cdc13-Stn1-Ten1 Simultaneously Activates DNA Damage and Spindle Checkpoints

Telomeres, the ends of eukaryotic linear chromosomes, are composed of repeated DNA sequences and specialized proteins, with the conserved telomeric Cdc13/CTC1-Stn1-Ten1 (CST) complex providing chromosome stability via telomere end protection and the regulation of telomerase accessibility. In this st...

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Bibliographic Details
Main Authors: Nathalie Grandin, Michel Charbonneau
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/19/1605
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