PPE50 variants as novel phylogeographic signatures of host-pathogen co-evolution in tuberculosis

PPE50 is a diverse novel subfamily of PE/PPE proteins in the Mycobacterium tuberculosis complex that show a phylogeographic distribution indicative host-pathogen co-evolution.

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Bibliographic Details
Main Authors: Christopher D’Souza, Jody E. Phelan, Paula-Josefina Gomez-Gonzalez, Joseph Thorpe, Taane G. Clark, Anthony G. Tsolaki
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08383-3
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