Enhanced Small Extracellular Vesicle Uptake by Activated Interneurons Improves Stroke Recovery in Mice

Enhanced Small Extracellular Vesicle Uptake by Activated Interneurons Improves Stroke Recovery in Mice

ABSTRACT Neuronal circuitry remodelling, which comprises excitatory and inhibitory neurons, is critical for improving neurological outcomes after a stroke. Preclinical studies have shown that small extracellular vesicles (sEVs) have a therapeutic effect on stroke recovery. However, it is highly chal...

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Bibliographic Details
Main Authors: Mingjin Wang, Zhongwu Liu, Weida Wang, Michael Chopp, Michael Millman, Yanfeng Li, Pasquale Cepparulo, Amy Kemper, Chao Li, Li Zhang, Yi Zhang, Zheng Gang Zhang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of Extracellular Biology
Subjects:
axonal remodelling
interneurons
small extracellular vesicles
stroke
Online Access:https://doi.org/10.1002/jex2.70036
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https://doi.org/10.1002/jex2.70036

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