Prednisolone impairs trabecular bone score changes in adolescents with 21-hydroxylase deficiency

Prednisolone impairs trabecular bone score changes in adolescents with 21-hydroxylase deficiency

Background Individuals with 21-hydroxylase deficiency (21OHD) require lifelong glucocorticoid (GC) therapy, which increases their risk of fragility fractures. However, fractures in GC-treated individuals can occur at normal bone mineral density (BMD) levels, suggesting an alteration in the bone micr...

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Bibliographic Details
Main Authors: Pattara Wiromrat, Yutapong Raruenrom, Phanpaphorn Namphaisan, Nantaporn Wongsurawat, Ouyporn Panamonta, Chatlert Pongchaiyakul
Format: Article
Language:English
Published: The Korean Pediatric Society 2025-03-01
Series:Clinical and Experimental Pediatrics
Subjects:
adolescents
21-hydroxylase deficiency
glucocorticoid
trabecular bone score
Online Access:http://e-cep.org/upload/pdf/cep-2024-01060.pdf
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http://e-cep.org/upload/pdf/cep-2024-01060.pdf

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