Identification of progression related LncRNAs in colorectal cancer aggressiveness

Identification of progression related LncRNAs in colorectal cancer aggressiveness

Abstract Colorectal cancer (CRC) progression involves complex molecular alterations, including the dysregulation of long non-coding RNAs (lncRNAs). In this study, we identified key progression-related lncRNAs in CRC by integrating transcriptomic data from TCGA and single-cell RNA sequencing (scRNA-s...

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Bibliographic Details
Main Authors: Wei Xi, Xinxin Sun, Mingwei Wang, Xizi Wang, Kun Li, Runze Jiang, Xiaodong Jia, Wenxiao Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Colorectal cancer
LncRNAs
Cancer progression
Tumor microenvironment
Immune regulation
Immune infiltration
Online Access:https://doi.org/10.1038/s41598-025-02096-7
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https://doi.org/10.1038/s41598-025-02096-7

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