Electron transfer engineering of artificially designed cell factory for complete biosynthesis of steroids

Abstract Biosynthesis of steroids by artificially designed cell factories often involves numerous nicotinamide adenine dinucleotide phosphate (NADPH)-dependent enzymes that mediate electron transfer reactions. However, the unclear mechanisms of electron transfer from regeneration to the final delive...

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Bibliographic Details
Main Authors: Qihang Chen, Wenqian Wei, Zikai Chao, Rui Qi, Jianhong He, Huating Chen, Ke Wang, Xinglong Wang, Yijian Rao, Jingwen Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58926-9
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