Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes in C. elegans
Abstract Therapeutic use of tiny extracellular vesicles (EVs) requires understanding cargo loading mechanisms. Here, we use a modular proximity labeling approach to identify the cargo of ciliary EVs associated with the transient receptor potential channel polycystin-2 PKD-2 of C. elegans. Polycystin...
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| Main Authors: | Inna A. Nikonorova, Elizabeth desRanleau, Katherine C. Jacobs, Josh Saul, Jonathon D. Walsh, Juan Wang, Maureen M. Barr |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-57512-3 |
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