The Clinical Validity and Utility of PCR Compared to Conventional Culture and Sensitivity Testing for the Management of Complicated Urinary Tract Infections in Adults: A Secondary (Ad Hoc) Analysis of Pathogen Detection, Resistance Profiles, and Impact on Clinical Outcomes

The Clinical Validity and Utility of PCR Compared to Conventional Culture and Sensitivity Testing for the Management of Complicated Urinary Tract Infections in Adults: A Secondary (Ad Hoc) Analysis of Pathogen Detection, Resistance Profiles, and Impact on Clinical Outcomes

Clinical success in treating complicated urinary tract infections (cUTIs) depends on accurate pathogen detection, given the common occurrence of polymicrobial infections and antimicrobial resistance. This multicenter, randomized, investigator-blinded study compared polymerase chain reaction (PCR)-ba...

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Bibliographic Details
Main Authors: Moustafa Kardjadj, Tara W. Chang, Roel Chavez, DeAndre Derrick, Frank L. Spangler, Itoe P. Priestly, Lauren Y. Park, Thomas K. Huard
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
Subjects:
urinary tract infection
polymerase chain reaction
microbial sensitivity tests
antimicrobial drug resistance
polymicrobial infections
molecular diagnostic testing
Online Access:https://www.mdpi.com/2076-2607/13/4/949
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