RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein

RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein

The RING finger protein 5 (RNF5), an E3 ubiquitin ligase, has demonstrated significant antiviral activity against various viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Kaposi’s sarcoma-associated herpesvirus (KSHV). However, its role in hepatitis B virus (HBV) r...

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Bibliographic Details
Main Authors: Jing Xu, Hongxiao Song, Fengchao Xu, Yanli Gao, Hongyu Jiang, Guangyun Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Microbiology
Subjects:
RNF5
HBV - hepatitis B virus
core protein
Caspase-3
E3 ubiqitin ligase
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1548061/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1548061/full

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