Variations of blood D-serine and D-aspartate homeostasis track psychosis stages

Variations of blood D-serine and D-aspartate homeostasis track psychosis stages

Abstract Schizophrenia (SCZ) is a severe psychotic disorder characterized by a disruption in glutamatergic NMDA receptor (NMDAR)-mediated neurotransmission. Compelling evidence has revealed that NMDAR activation is not limited to L-glutamate, L-aspartate, and glycine since other free amino acids (AA...

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Main Authors: Antonio Rampino, Martina Garofalo, Tommaso Nuzzo, Maria Favia, Silvia Saltarelli, Rita Masellis, Martina Grazia Asselti, Teresa Claudia Pennacchio, Dario Bruzzese, Francesco Errico, Matteo Vidali, Alessandro Bertolino, Alessandro Usiello
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-024-00537-2
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https://doi.org/10.1038/s41537-024-00537-2

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