Rnd3 deletion affects neuroblast behavior through the RhoA/ROCK pathway but not neural stem cells in postnatal mice subventricular zone

Rnd3 deletion affects neuroblast behavior through the RhoA/ROCK pathway but not neural stem cells in postnatal mice subventricular zone

In the subventricular zone (SVZ), neural stem cells (NSCs) generate neural progenitor cells (NPCs), which proliferate and differentiate into neuroblasts (NBs) that will travel along the rostral migratory stream (RMS) to the olfactory bulbs (OBs), where they mature into interneurons. Rnd3, a member o...

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Bibliographic Details
Main Authors: Amalia Solana-Orts, Germán Belenguer, Begoña Ballester-Lurbe, Olga Gómez, Ignacio Pérez-Roger, José Terrado, Enric Poch, Alexandra Bizy
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
subventricular zone (SVZ)
Rnd3/ RhoE
neural stem cell (NSC)
neuroblast migration
RhoA/ROCK pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1612177/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1612177/full

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