Size- and polymer-dependent toxicity of amorphous environmentally relevant micro- and nanoplastics in human bronchial epithelial cells

Size- and polymer-dependent toxicity of amorphous environmentally relevant micro- and nanoplastics in human bronchial epithelial cells

Abstract Background Knowledge of the toxicological impact of micro- and nanoplastics (MNPs) on the human airway epithelium is limited and almost exclusively based on experiments applying high doses of spherical polystyrene (PS) particles. In this study, we investigated the toxicity of a broad size r...

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Main Authors: I. F. Gosselink, P. Leonhardt, E. M. Höppener, R. Smelt, M. J. Drittij, M. Davigo, G. G. H. van den Akker, I. M. Kooter, T. J. M. Welting, F. J. van Schooten, A. H. V. Remels
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Microplastics and Nanoplastics
Subjects:
Inhalation toxicology
Polypropylene
Polyamide
Polyvinylchloride
Inflammation
NF-ĸB
Online Access:https://doi.org/10.1186/s43591-025-00126-9
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https://doi.org/10.1186/s43591-025-00126-9

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