Protracted Tonsillitis as an Atypical Initial Manifestation of Methotrexate-Induced EBV-Positive Lymphoproliferative Disorder in Rheumatoid Arthritis: A Case Report and Literature Review

Protracted Tonsillitis as an Atypical Initial Manifestation of Methotrexate-Induced EBV-Positive Lymphoproliferative Disorder in Rheumatoid Arthritis: A Case Report and Literature Review

<b>Background and Clinical Significance:</b> Methotrexate is widely used as a disease-modifying antirheumatic drug for rheumatoid arthritis (RA), yet prolonged immunosuppression may lead to rare complications, including Epstein–Barr virus (EBV)-positive lymphoproliferative disorders (LPD...

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Bibliographic Details
Main Authors: Ting-Shen Lin, Tang-Yi Tsao, Shih-Wei Chen, Min-Cheng Ko, Stella Chin-Shaw Tsai
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Diagnostics
Subjects:
methotrexate
lymphoproliferative disorder
tonsillitis
rheumatoid arthritis
immunosuppression
Online Access:https://www.mdpi.com/2075-4418/15/12/1517
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