Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

Background and aimsThe psychostimulant actions of amphetamine (AMPH) have been correlated with its ability to orchestrate ventral tegmental area (VTA) dopamine (DA) neuron activity states and, thus, DA release in output regions: in rats, a single exposure is sufficient to reduce the fraction of spon...

Full description

Saved in:
Bibliographic Details
Main Authors: Ornella Valenti, Katarzyna Anna Rekawek, Sophie Wieser, Hilal Bulut, Petra Scholze, Stefan Boehm
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
amygdala
amphetamine
avoidance behavior
dopamine neurons
metabotropic glutamate receptors
nucleus accumbens
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1534101/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2025.1534101/full

Similar Items