Timosaponin AIII inhibits gastric cancer by causing oxidative stress and blocking autophagic flux

Timosaponin AIII inhibits gastric cancer by causing oxidative stress and blocking autophagic flux

Background: : Gastric cancer (GC) is a prevalent malignant tumor worldwide, with limited treatment targets. Timosaponin AIII (Tim AIII) is the naturally steroid saponin isolated from Anemarrhena, while this study initially confirms the anti-GC effect of Tim AIII. Methods: : MTT assay, cell cycle ana...

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Bibliographic Details
Main Authors: Chunyang Zhu, Shuming Chen, Yangyang Lu, Jialin Song, Shasha Wang, Jing Guo, Xiaoxi Han, YuanYuan Fang, Siyi Zhang, Wensheng Qiu, Weiwei Qi
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Translational Oncology
Subjects:
Gastric cancer
Oxidative stress
Autophagic flux
ROS
Timosaponin AIII
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325002128
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