L-glutaminase synthesis by Klebsiella pneumoniae (AS KP 23) isolated from clinical strain, and its efficacy against human hepatocellular and breast cancer cell lines
Abstract Background Cancer is a major cause of morbidity and mortality worldwide. The proliferation of cancer cells depends largely on glutamine for survival and proliferation. Glutamine serves as a carbon source for the synthesis of metabolites and lipids via the TCA cycle, as well as a source of n...
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Main Authors: | Lina J. Abdel-Hafez, Eman Y. T. Elariny, Asmaa E. Ibrahim, Mahmoud E. F. Abdel-Haliem |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | BMC Microbiology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12866-025-03773-3 |
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