L-glutaminase synthesis by Klebsiella pneumoniae (AS KP 23) isolated from clinical strain, and its efficacy against human hepatocellular and breast cancer cell lines

Abstract Background Cancer is a major cause of morbidity and mortality worldwide. The proliferation of cancer cells depends largely on glutamine for survival and proliferation. Glutamine serves as a carbon source for the synthesis of metabolites and lipids via the TCA cycle, as well as a source of n...

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Bibliographic Details
Main Authors: Lina J. Abdel-Hafez, Eman Y. T. Elariny, Asmaa E. Ibrahim, Mahmoud E. F. Abdel-Haliem
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-025-03773-3
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