KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Abstract Innovative therapeutic approaches for heart failure, a leading cause of mortality worldwide, are urgently needed. In this study, the important role of Krüppel‐like factor 1 (KLF1) in cardiomyocyte proliferation and heart regeneration is explored, and revealed its ability to regulate the Wnt...

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Main Authors: Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
cardiomyocyte proliferation and heart regeneration
heart failure
KLF1
Wnt/β‐catenin signaling pathway
Online Access:https://doi.org/10.1002/advs.202413964
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https://doi.org/10.1002/advs.202413964

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