Distinct microbiota composition and dendritic cell activation in the appendix microenvironment of ulcerative colitis patients

Distinct microbiota composition and dendritic cell activation in the appendix microenvironment of ulcerative colitis patients

Appendectomy has been associated with reduced risk of developing ulcerative colitis (UC) or experiencing flares after diagnosis, suggesting the appendix may play a role in UC pathogenesis. Given its function in microbial homeostasis and gut immunity, we investigated the relationship between mucosal...

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Bibliographic Details
Main Authors: Melania Scarpa, Ignazio Castagliuolo, Ilaria Patuzzi, Andromachi Kotsafti, Astghik Stepanyan, Claudia Armellin, Giovanni Tagliente, Edoardo Savarino, Fabiana Zingone, Cesare Ruffolo, Luca Saadeh, Gaya Spolverato, Imerio Angriman, Marco Scarpa
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Appendix
ulcerative colitis
microbiota
dendritic cells
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2545416
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2545416

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