Evaluation of tolvaptan-associated hepatic disorder using different national pharmacovigilance databases

Abstract Tolvaptan-associated hepatic disorder is a rare, but lethal adverse event; however, the precise risk and time of onset remain unclear. This study aimed to characterize the severity, time‑to‑onset, and outcomes of hepatic disorder based on patient age and sex. Patient data were acquired from...

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Bibliographic Details
Main Authors: Takaya Uno, Kouichi Hosomi, Satoshi Yokoyama
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-77052-y
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