Single-cell RNA sequencing reveals key signaling pathways and biological functions in giant cell tumors of bone

Abstract Background Giant cell tumor of bone (GCTB) represents a group of tumors that characterized by their heterogeneity and the presence of multiple cell types. It is essential to understand their molecular mechanisms for better designing therapeutic approaches. Methods We applied single cell RNA...

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Bibliographic Details
Main Authors: Zuozhuan Lin, Zuoxi Chen
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-02353-1
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