Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes
Abstract The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein‐coupled receptors (GPCRs) have been reported to activate MEF2, but a comprehensive analysis of GPCR activators that regulate MEF2 has to our knowl...
Saved in:
| Main Authors: | András D Tóth, Richard Schell, Magdolna Lévay, Christiane Vettel, Philipp Theis, Clemens Haslinger, Felix Alban, Stefanie Werhahn, Lina Frischbier, Jutta Krebs‐Haupenthal, Dominique Thomas, Hermann‐Josef Gröne, Metin Avkiran, Hugo A Katus, Thomas Wieland, Johannes Backs |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2018-06-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201708536 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
EFFECT OF SEVOFLURANE EXPOSURE ON ADRIAMYCIN-INDUCED INJURIES TO MYOCYTES
by: Li-hua Fan, et al.
Published: (2014-01-01) -
Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells
by: Tsukasa Koide, et al.
Published: (2025-06-01) -
MEF2A, MEF2C, and MEF2D as potential biomarkers of pancreatic cancer?
by: Chunxia Zhai, et al.
Published: (2025-04-01) -
The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies
by: Hannah M. Hicks, et al.
Published: (2024-12-01) -
The novelty of profilin 2 in regulating pyruvate kinase M2 nuclear translocation and promoting tumor angiogenesis in lung adenocarcinoma
by: Xiaohui Du, et al.
Published: (2025-05-01)