Identification of HMOX-1-Targeting Natural Compounds in <i>Camellia nitidissima</i> Chi for NSCLC Therapy: Integrating Bioassay and In Silico Screening Approaches

Identification of HMOX-1-Targeting Natural Compounds in <i>Camellia nitidissima</i> Chi for NSCLC Therapy: Integrating Bioassay and In Silico Screening Approaches

<b>Background/Objectives:</b> <i>Camellia nitidissima</i> Chi (<i>C. nitidissima</i>), a traditional Chinese “food and medicine homology” plant, has demonstrated potential anti-tumor properties. However, its mechanisms of anti-lung cancer activity via ferroptosis...

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Main Authors: Lingqiu Zhang, Fan Zhang, Haimei Liang, Xiangling Qin, Chunmei Liang, Manlu Zhong, Yuemi Mo, Jinling Xie, Xiaotao Hou, Jiagang Deng, Erwei Hao, Zhengcai Du
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceuticals
Subjects:
<i>Camellia nitidissima</i> leaves
ferroptosis
NSCLC
bioactive screening
preparative separation
Online Access:https://www.mdpi.com/1424-8247/18/6/824
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