Pericoronary adipose tissue attenuation predicts compositional plaque changes: a 12-month longitudinal study in individuals with type 2 diabetes without symptoms or known coronary artery disease

Pericoronary adipose tissue attenuation predicts compositional plaque changes: a 12-month longitudinal study in individuals with type 2 diabetes without symptoms or known coronary artery disease

Abstract Background Pericoronary adipose tissue attenuation (PCATa), derived from coronary computed tomography angiography (CCTA), is a novel marker of inflammation in the coronary arteries. Patients with type 2 diabetes mellitus (T2DM) are at elevated risk of coronary artery disease (CAD), potentia...

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Main Authors: Katrine Schultz Overgaard, Thomas Rueskov Andersen, Laurits Juhl Heinsen, Gokulan Pararajasingam, Roda Abdulkadir Mohamed, Freja Sønder Madsen, Irmelin Irene Aagaard Biesenbach, Kurt Højlund, Jess Lambrechtsen, Søren Auscher, Kenneth Egstrup
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cardiovascular Diabetology
Subjects:
Pericoronary adipose tissue
Inflammation
Type 2 diabetes mellitus
Coronary CT angiography
Coronary artery disease
Atherosclerosis progression
Online Access:https://doi.org/10.1186/s12933-025-02694-9
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https://doi.org/10.1186/s12933-025-02694-9

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