Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11

Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11

Summary: Appropriate cellular recognition of viruses is essential for the generation of an effective innate and adaptive immune response. Viral sensors and their downstream signaling components thus provide a crucial first line of host defense. Many of them exhibit subcellular relocalization upon ac...

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Main Authors: Benjamin J. Ravenhill, Marisa Oliveira, George Wood, Ying Di, Joanne Kite, Xinyue Wang, Colin T.R. Davies, Yongxu Lu, Robin Antrobus, Gill Elliott, Nerea Irigoyen, David J. Hughes, Paul A. Lyons, Betty Chung, Georg H.H. Borner, Michael P. Weekes
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725000348
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http://www.sciencedirect.com/science/article/pii/S2211124725000348

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