Montelukast reduced docetaxel-induced peripheral neuropathy in rats by altering oxidative stress, histopathological damage, and gene expressions

Peripheral neuropathy (PN) is a common side effect of docetaxel (DTX). In this study, we aimed to evaluate the effects of montelukast (MNT), a leukotriene receptor antagonist drug, against DTX-induced PN in rats. Thirty-two male rats were divided into four groups and treated for four weeks: control...

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Bibliographic Details
Main Authors: M.D. Karakoç, Ö. Özmen, M.N. Zengin, O. Çiftçi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2025-05-01
Series:Brazilian Journal of Medical and Biological Research
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100644&lng=en&tlng=en
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