Tumor-microenvironment and molecular biology of classic Hodgkin lymphoma in children, adolescents, and young adults

Classic Hodgkin lymphoma (cHL) exhibits a bimodal age distribution with incidence peaks in adolescents and young adults (AYAs) aged 15-39 years and in older adults over 50 years. The unique biology of cHL, characterized by a tumor microenvironment (TME) composed predominantly of non-malignant immune...

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Bibliographic Details
Main Authors: Tomohiro Aoki, Kyle Wierzbicki, Suhong Sun, Christian Steidl, Lisa Giulino-Roth
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1515250/full
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