Recent insights into the cellular mechanisms of acute pancreatitis
In acute pancreatitis, initiating cellular events causing acinar cell injury includes co-localization of zymogens with lysosomal hydrolases, leading to premature enzyme activation and pathological exocytosis of zymogens into the interstitial space. This is followed by processes that accentuate cell...
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Main Authors: | Laura I Cosen-Binker, Herbert Y Gaisano |
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Format: | Article |
Language: | English |
Published: |
Wiley
2007-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/2007/930424 |
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