Berberine treatment inhibits ferroptosis in NIT-1 murine pancreatic cell line via inhibiting OGT expression levels

Abstract Recently, the prevalence of diabetes mellitus (DM) in the world continues to rise, which has seriously threatened human health. Enhanced pancreatic β-cell death is one of the important factors in the pathogenesis of type 1 diabetes mellitus (T1DM). Berberine, an alkaloid, plays a series of...

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Bibliographic Details
Main Authors: Chengbi Yu, Yue Qiu, Dongbiao Yan, Wendi Zhou, Jin Wan, Jiewei Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-03537-z
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