Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Abstract Yersinia pestis, the causative agent of plague, remains a significant global health hazard and a potential top‐tier biothreat despite modern medical advances. Here, two mRNA constructs encoding different versions of the low‐calcium response virulence (LcrV) protective antigen, an essential...

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Main Authors: Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
lipid nanoparticles
mRNA
vaccine
Y. pestis
Online Access:https://doi.org/10.1002/advs.202501286
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https://doi.org/10.1002/advs.202501286

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