Landscape of small nucleic acid therapeutics: moving from the bench to the clinic as next-generation medicines

Abstract The ability of small nucleic acids to modulate gene expression via a range of processes has been widely explored. Compared with conventional treatments, small nucleic acid therapeutics have the potential to achieve long-lasting or even curative effects via gene editing. As a result of recen...

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Bibliographic Details
Main Authors: Mohan Liu, Yusi Wang, Yibing Zhang, Die Hu, Lin Tang, Bailing Zhou, Li Yang
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-02112-8
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