Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation

Introduction: Holothurian glycosaminoglycan (hGAG) is an extract from the body wall of sea cucumber and previous studies have proved many unique bioactivities of it, such as anti-tumor, anti-coagulation and immune regulation. Previous studies of our research group have shown hGAG promoted cell apopt...

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Bibliographic Details
Main Authors: Dai Hao-yu MM, Liu Ting-ting MM, Cao Yi-wei MM, Sui Ai-hua MM, Yang Xiao-hui MD, Lin Cun-zhi MD
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Integrative Cancer Therapies
Online Access:https://doi.org/10.1177/15347354251341442
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