Arsenic trioxide regulates DYNAP through hsa-mir-573 and inhibits the proliferation of laryngeal cancer

Arsenic trioxide regulates DYNAP through hsa-mir-573 and inhibits the proliferation of laryngeal cancer

Abstract Laryngeal squamous cell carcinoma (LSCC) is a malignant tumor with limited treatment options and poor prognosis in advanced stages. Arsenic trioxide (ATO), a drug well-known for treating acute promyelocytic leukemia, has shown potential antitumor effects in several solid tumors. This study...

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Bibliographic Details
Main Authors: Yanru Ren, Xiao Yang, Yang Hui, Weiyao Chen, Yi Cheng, Ning Zhang, Tao Liu, Xinxin Yang, Xiaoyu Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Laryngeal cancer
Proliferative capacity
Arsenic trioxide
Hsa-mir-573
Dynactin-associated protein
PI3K/AKT pathway
Online Access:https://doi.org/10.1038/s41598-025-12881-z
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https://doi.org/10.1038/s41598-025-12881-z

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