Predicting gene expression changes upon epigenomic drug treatment [version 3; peer review: 4 approved, 2 not approved]

Background Tumors are characterized by global changes in epigenetic modifications such as DNA methylation and histone modifications that are functionally linked to tumor progression. Accordingly, several drugs targeting the epigenome have been proposed for cancer therapy, notably, histone deacetylas...

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Bibliographic Details
Main Authors: Monjura Afrin Rumi, Vishaka Gopalan, Sridhar Hannenhalli, Piyush Agrawal
Format: Article
Language:English
Published: F1000 Research Ltd 2025-05-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/12-1089/v3
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