ONTraC characterizes spatially continuous variations of tissue microenvironment through niche trajectory analysis
Abstract Recent technological advances enable mapping of tissue spatial organization at single-cell resolution, but methods for analyzing spatially continuous microenvironments are still lacking. We introduce ONTraC, a graph neural network-based framework for constructing spatial trajectories at nic...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03588-5 |
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