Enterobacterales use capsules, transporters, mobile genetic elements, and other evolutionary adaptations to survive antibiotics exposure in the absence of resistance genes

Carbapenems and colistin are last-resort antibiotics used to manage difficult-to-treat infections caused by Gram-negative bacteria. However, resistance to these two antibiotics is rising globally, and there is limited knowledge on how pathogens evolve resistance when known resistance genes are absen...

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Bibliographic Details
Main Authors: Masego Mmatli, Nontombi Marylucy Mbelle, Bernard Fourie, John Osei Sekyere
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2514092
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