YY1-induced DDX18 modulates EMT via the AKT/mTOR pathway in esophageal cancer: a novel therapeutic target

YY1-induced DDX18 modulates EMT via the AKT/mTOR pathway in esophageal cancer: a novel therapeutic target

Abstract Background Esophageal cancer is the 11th most common malignancy and the 7th leading cause of cancer-related death globally. Identifying key molecules and underlying mechanisms in the progression of esophageal cancer represents an effective strategy for developing novel therapeutic approache...

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Bibliographic Details
Main Authors: Xiaochao Ma, Yulu He, Yue Yang, Tianyu Lu, Ze Tang, Youbin Cui, Rui Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
DDX18
Esophageal cancer
Transcription factor
EMT
Apoptosis
Online Access:https://doi.org/10.1186/s12967-025-06555-7
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https://doi.org/10.1186/s12967-025-06555-7

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