Notch activity is modulated by the aGPCR Latrophilin binding the DSL ligand in C. elegans

Notch activity is modulated by the aGPCR Latrophilin binding the DSL ligand in C. elegans

Abstract The Notch pathway is a highly conserved signaling cascade across metazoans that regulates numerous physiological processes, including cell proliferation, differentiation, and fate determination. Given its fundamental roles, the pathway is tightly regulated by diverse molecules through multi...

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Main Authors: Willem Berend Post, Victoria Elisabeth Groß, Daniel Matúš, Iannis Charnay, Fabian Liessmann, Florian Seufert, Peter Hildebrand, Jens Meiler, Anette Kaiser, Torsten Schöneberg, Simone Prömel
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61730-0
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https://doi.org/10.1038/s41467-025-61730-0

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