Blood transcriptomics to characterize key biological pathways and identify biomarkers for predicting mortality in melioidosis

Melioidosis is an often lethal tropical disease caused by the Gram-negative bacillus, Burkholderia pseudomallei. The study objective was to characterize transcriptomes in melioidosis patients and identify genes associated with outcome. Whole blood RNA-seq was performed in a discovery set of 29 melio...

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Main Authors: Thatcha Yimthin, Jacqueline Margaret Cliff, Rungnapa Phunpang, Peeraya Ekchariyawat, Taniya Kaewarpai, Ji-Sook Lee, Clare Eckold, Megan Andrada, Ekkachai Thiansukhon, Kittisak Tanwisaid, Somchai Chuananont, Chumpol Morakot, Narongchai Sangsa, Wirayut Silakun, Sunee Chayangsu, Noppol Buasi, Nicholas Day, Ganjana Lertmemongkolchai, Wasun Chantratita, T. Eoin West, Narisara Chantratita
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
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Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1858176
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