A medium-chain fatty acid analogue prevents endotoxin liver injury in a murine model

A medium-chain fatty acid analogue prevents endotoxin liver injury in a murine model

Abstract Parenteral nutrition (PN) is lifesaving for patients with short bowel syndrome and other gastrointestinal disorders, however long-term use may lead to complications including hepatosteatosis and sepsis. We have previously demonstrated the anti-steatotic, -fibrotic, and -inflammatory propert...

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Bibliographic Details
Main Authors: Sarah Z. Wang, Thomas I. Hirsch, Scott C. Fligor, Savas T. Tsikis, Amy Pan, Mikayla Quigley, Paul D. Mitchell, Kathleen M. Gura, David A. Fraser, Mark Puder
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Parenteral nutrition
Liver steatosis
Inflammation
Fatty acid
Online Access:https://doi.org/10.1038/s41598-025-98200-y
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https://doi.org/10.1038/s41598-025-98200-y

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