Proteus mirabilis exacerbates ulcerative colitis by inhibiting mucin production

Proteus mirabilis exacerbates ulcerative colitis by inhibiting mucin production

IntroductionUlcerative colitis (UC) is characterized by chronic inflammation and ulceration in colonic mucosa, accompanied by a defective epithelial barrier. Proteus mirabilis (P. mirabilis) bacterium is a putative intestinal pathogen with invasive ability, yet its role in UC inflammation and gut ba...

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Bibliographic Details
Main Authors: Zhihui Jiang, Pengpeng Li, Kehui Qiu, Yang Liao, Xin Chen, Ji Xuan, Fangyu Wang, Hongfeng Ma, Ye Wang, Minsheng Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
ulcerative colitis
Proteus mirabilis
mucus layer
IL-18
bacteriophage
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1556953/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1556953/full

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