SrHPO4-coated Mg alloy implant attenuates postoperative pain by suppressing osteoclast-induced sensory innervation in osteoporotic fractures

SrHPO4-coated Mg alloy implant attenuates postoperative pain by suppressing osteoclast-induced sensory innervation in osteoporotic fractures

Osteoporotic fractures have become a common public health problem and are usually accompanied by chronic pain. Mg and Mg-based alloys are considered the next-generation orthopedic implants for their excellent osteogenic inductivity, biocompatibility, and biodegradability. However, Mg-based alloy can...

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Main Authors: Guobin Qi, Zengxin Jiang, Jialin Niu, Chang Jiang, Jian Zhang, Jia Pei, Xiao Wang, Senbo An, Tao Yu, Xiuhui Wang, Yueqi Zhang, Tianle Ma, Xiaotian Zhang, Guangyin Yuan, Zhe Wang
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Materials Today Bio
Subjects:
Osteoporotic fracture
Mg alloy
SrHPO4 coating
Osteoclast
Sensory innervation
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424002886
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