Involvement of polymorphisms of TNF, CRP and SAA1 genes in the predisposition to the development of ankylosing spondylitis and its clinical manifestations

Involvement of polymorphisms of TNF, CRP and SAA1 genes in the predisposition to the development of ankylosing spondylitis and its clinical manifestations

Objective. To study the involvement of the rs1800629 G/A polymorphisms of the TNF-α gene, rs1205C/T of the CRP gene, and rs12218T/C of the SAA1 gene in the predisposition to ankylosing spondylitis (AS) and their role in the formation of clinical phenotypes of AS.Materials and methods. 122 patients w...

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Bibliographic Details
Main Authors: M. Yu. Krylov, I. A. Guseva, K. V. Sakharova, E. Yu. Samarkina, S. F. Erdes, N. V. Konovalova, D. A. Varlamov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2022-03-01
Series:Научно-практическая ревматология
Subjects:
ankylosing spondylitis
polymorphism
tnf-α gene
crp gene
saa1 gene
enthesitis
peripheral arthritis
Online Access:https://rsp.mediar-press.net/rsp/article/view/3118
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