Protective Efficacy of Decreasing Antigen Doses of a <i>Chlamydia abortus</i> Subcellular Vaccine Against Ovine Enzootic Abortion in a Pregnant Sheep Challenge Model

Protective Efficacy of Decreasing Antigen Doses of a <i>Chlamydia abortus</i> Subcellular Vaccine Against Ovine Enzootic Abortion in a Pregnant Sheep Challenge Model

Background/Objective: <i>Chlamydia abortus</i>, the cause of ovine enzootic abortion, is a zoonotic bacterial pathogen and one of the most infectious causes of foetal death in sheep worldwide. Although the disease can be controlled using commercial inactivated and live whole-organism vac...

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Bibliographic Details
Main Authors: Morag Livingstone, Kevin Aitchison, Javier Palarea-Albaladejo, Francesco Ciampi, Clare Underwood, Antonia Paladino, Francesca Chianini, Gary Entrican, Sean Ranjan Wattegedera, David Longbottom
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
<i>Chlamydia abortus</i>
ovine enzootic abortion
vaccine development
vaccine efficacy
quantitative real-time PCR
serological analysis
Online Access:https://www.mdpi.com/2076-393X/13/1/89
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