Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlas

Gene co-expression network inference from bulk tissue samples often misses cell-type-specific interactions, which can be detected through single-cell gene expression data. However, the noise and sparsity of single-cell data challenge the inference of these networks. We developed scNET, a framework f...

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Bibliographic Details
Main Authors: Euijeong Sung, Junha Cha, Seungbyn Baek, Insuk Lee
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Animal Cells and Systems
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Online Access:https://www.tandfonline.com/doi/10.1080/19768354.2025.2472002
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