Biological potential of Lophosoria quadripinnata fern extract: integration of UHPLC/ESI/QToF/MS analysis, antioxidant activity, molecular docking and molecular dynamics simulation

Biological potential of Lophosoria quadripinnata fern extract: integration of UHPLC/ESI/QToF/MS analysis, antioxidant activity, molecular docking and molecular dynamics simulation

Lophosoria quadripinnata (J.F.Gmel.) C.Chr., a fern species from the Dicksoniaceae family, is widely distributed in Central and South America. This study aimed to identify the bioactive compounds in the aqueous extract of L. quadripinnata, evaluate its antioxidant potential through in vitro analysis...

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Main Authors: Alfredo Torres-Benítez, José Erick Ortega-Valencia, Juan Rodrigo Salazar, Jaqueline Ley-Martínez, Javian Gallardo-Valdivia, Marta Sánchez, María Pilar Gómez-Serranillos, Gabriel Vargas-Arana, Mario J. Simirgiotis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
fern
lophosoria
extract
metabolites
antioxidant potential
enzymatic inhibition
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1611733/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1611733/full

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