CRISPRi knockdown of mycobacterial tkt gene potentiates the anti-mycobacterial activity of phyto-compounds from selected medicinal plants
Abstract Background Mycobacterium tuberculosis (Mtb) infection is well known to be challenging to treat. Treatment effectiveness is restricted by the pathogen’s inherent drug resistance. A deeper understanding of essential bacterial pathways that influence Mtb growth and survival can expediate the d...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Complementary Medicine and Therapies |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12906-025-04987-8 |
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