The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review

Neurons and glia respond to acute injury by participating in the CNS innate immune response. This involves the recognition and clearance of “not self ” pathogens and “altered self ” apoptotic cells. Phagocytic receptors (CD14, CD36, TLR–4) clear “not self” pathogens; neurons and glia express “deat...

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Bibliographic Details
Main Authors: M. R. Griffiths, P. Gasque, J. W. Neal
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.4061/2010/151097
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